推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 147 kDa
种属反应性
rat, mouse, human
浓度
~1 mg/mL
技术
ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... PTPRC(5788)
一般描述
CD45（分化簇45）基因定位于人类染色体1q31.3-q32.1。它编码一型跨膜蛋白，并和其前体一起在成核的造血细胞中表达。该蛋白由多个胞外结构域和一个高度保守的胞内结构域组成。
抗-CD45 抗体检测内源性总 CD45 蛋白水平。
免疫原
针对人源 CD45 的合成肽产生抗血清。
免疫原范围：981-1030
免疫原范围：981-1030
应用
兔抗CD45抗体可用于：
- 免疫组织化学染色
- 免疫荧光染色
- 免疫染色
生化/生理作用
CD45 编码的蛋白（分化抗原簇 45）是一个原型受体，具有磷酸酶活性。研究发现 CD45 控制 T 细胞介导的 BCR 信号传导。
分化簇45 (CD45)促进淋巴细胞信号传导和SRC家族激酶Lck的调控。这种蛋白质参与了几种哺乳动物的多态性。
特点和优势
您可完全放心的评估我们的抗体。如果抗体在您的应用中没有发挥效果，我们将给予您完全的赔偿或更换抗体。 了解更多。
外形
兔IgG，溶于磷酸盐缓冲盐水（不含Mg2+和Ca2+），pH 7.4，含150mM NaCl、0.02％叠氮化钠和50％甘油。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
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