推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen 82 kDa
种属反应性
mouse, human
浓度
~1 mg/mL
技术
ELISA: 1:20000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... PECAM1(5175)
一般描述
抗PECAM-1抗体检测内源性的总PECAM-1蛋白水平。
血小板内皮细胞粘附分子1(PECAM-1)基因长75-kb，位于人类17号染色体长臂上。该基因编码130-kD的一种免疫球蛋白超家族蛋白。这种蛋白是内皮细胞间连接(intercellular junction)的重要成分。PECAM1在循环血小板、单核细胞、中性粒细胞和某些T细胞亚群的表面表达。
免疫原
所制备的抗血清是针对人 PECAM-1 合成的肽。
免疫原范围： 686-735
免疫原范围： 686-735
生化/生理作用
血小板和内皮细胞粘附分子1（PECAM1）也称分化簇31（cluster of differentiation，CD31），它在炎症过程中的粘附级联（adhesion cascade）起关键作用，导致白细胞渗出。PECAM1对于通过血管内皮细胞的细胞间连接而实现的白细胞游出（leukocyte transmigration）至关重要。PECAM1的遗传多态性与动脉粥样硬化事件相关。PECAM1是一种膜糖蛋白，它促进同配和异配粘连。PECAM1 也与血管生成有关。
特点和优势
请在保持内心完全平静的情况下评估我们的抗体。如果抗体在您的使用中不起作用，我们将全额退款或提供新的抗体。了解更多。
外形
磷酸盐缓冲盐水中的兔IgG（不含 Mg2+ 和 Ca2+），pH7.4，150mM NaCl，0.02％ 叠氮化钠和 50％ 甘油。
免责声明
除非我们的目录或随附于产品的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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