推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 51 kDa
种属反应性
rat, human, mouse
浓度
~1 mg/mL
技术
ELISA: 1:10000
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... RXFP3(51289)
一般描述
Anti-RXFP3 Antibody detects endogenous levels of total RXFP3 protein.
RXFP3 (relaxin family peptide receptor 3) is also termed as GPCR 135/ SALPR (somatostatin- and angiotensin- like peptide receptor). It is distributed in the central nervous system (CNS), mainly in areas associated with memory, sensory and emotional processing. RXFP3 belongs to the insulin superfamily. This gene is mapped to human chromosome 5p13.
RXFP3 (relaxin family peptide receptor 3) is also termed as GPCR 135/ SALPR (somatostatin- and angiotensin- like peptide receptor). It is distributed in the central nervous system (CNS), mainly in areas associated with memory, sensory and emotional processing. RXFP3 belongs to the insulin superfamily. This gene is mapped to human chromosome 5p13.
免疫原
The antiserum was produced against synthesized peptide derived from human RXFP3.
Immunogen Range: 161-210
Immunogen Range: 161-210
生化/生理作用
RXFP3 (relaxin family peptide receptor 3) acts as the cognate receptor for relaxin-3. It controls feeding, motivated behaviors, stress and anxiety. RXFP3 system also modulates alcohol-seeking.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Hydrocarbon stapled B chain analogues of relaxin-3 retain biological activity.
Jayakody T, et al.
Peptides, 84, 44-57 (2016)
Role of relaxin-3/RXFP3 system in stress-induced binge-like eating in female rats.
Calvez J, et al.
Neuropharmacology, 102, 207-215 (2016)
5p13. 3p13. 2 duplication associated with developmental delay, congenital malformations and chromosome instability manifested as low-level aneuploidy.
Iourov IY, et al.
SpringerPlus, 4(1), 616-616 (2015)
In vitro pharmacological characterization of RXFP3 allosterism: an example of probe dependency.
Alvarez-Jaimes L, et al.
PLoS ONE, 7(2), e30792-e30792 (2012)
Philip J Ryan et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(51), 20789-20794 (2013-12-04)
Relapse and hazardous drinking represent the most difficult clinical problems in treating patients with alcohol use disorders. Using a rat model of alcohol use and alcohol-seeking, we demonstrated that central administration of peptide antagonists for relaxin family peptide 3 receptor
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