推荐产品
产品名称
Anti-MYC antibody produced in rabbit, affinity isolated antibody
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 48 kDa
种属反应性
rat, mouse, human
浓度
~1 mg/mL
技术
ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MYC(4609)
一般描述
The MYC (MYC proto-oncogene, bHLH transcription factor) gene is mapped to human chromosome 8q24.21. This gene encodes an oncogenic transcription factor and belongs to the MYC gene family. Anti-MYC antibody detects endogenous levels of total MYC protein.
免疫原
The antiserum was produced against synthesized peptide derived from human MYC.
Immunogen Range: 386-435
Immunogen Range: 386-435
应用
Anti-MYC antibody produced in rabbit has been used in western blotting.
生化/生理作用
MYC proto-oncogene, bHLH transcription factor (MYC) is known to induce tumor growth in a variety of cancer types. c-MYC overexpression promotes DNA replication, transcription, translation and metabolism in cancer cells. Upregulation of this gene is observed in pancreatic ductal adenocarcinoma and diffuse large B-cell lymphoma (DLBCL).
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Knockdown of ASF1B inhibits cell proliferation, migration, invasion and cisplatin resistance in gastric cancer through the Myc pathway.
Zhang, et al.
Oncology Letters, 25, 242-242 (2023)
c-MYC amplification and c-myc protein expression in pancreatic acinar cell carcinomas. New insights into the molecular signature of these rare cancers
La RS, et al.
Virchows Archiv, 9(5), 1-7 (2018)
PVT1 dependence in cancer with MYC copy-number increase
Tseng YY, et al.
Nature, 512(7512), 82-82 (2014)
Checkpoint suppressor 1 suppresses transcriptional activity of ERalpha and breast cancer cell proliferation via deacetylase SIRT1
Xu, Z, et al.
Cell Death & Disease, 9(5), 559-559 (2018)
Zhaowei Xu et al.
Cell death & disease, 9(5), 559-559 (2018-05-13)
Breast cancer is a highly heterogeneous carcinoma in women worldwide, but the underlying mechanisms that account for breast cancer initiation and development have not been fully established. Mounting evidence indicates that Checkpoint suppressor 1 (CHES1) is tightly associated with tumorigenesis
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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