推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 35 kDa
种属反应性
human
浓度
~1 mg/mL
技术
ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... MT-ND1(4535)
一般描述
Anti-MT-ND1 Antibody detects endogenous levels of total MT-ND1 protein.
MT-ND1 (mitochondrially encoded NADH dehydrogenase 1mt-Nd1) codes for NADH dehydrogenase-1.
MT-ND1 (mitochondrially encoded NADH dehydrogenase 1mt-Nd1) codes for NADH dehydrogenase-1.
免疫原
The antiserum was produced against synthesized peptide derived from human MT-ND1.
Immunogen Range: 176-225
Immunogen Range: 176-225
生化/生理作用
MT-ND1 (mitochondrially encoded NADH dehydrogenase 1mt-Nd1) plays a vital role in the electron transport chain of oxidative phosphorylation (OXPHOS). Mutations in MT-ND1 gene is observed in individuals with LHON (leber′s hereditary optic neuropathy). Mutation in MT-ND1 results in dextrocardia, ventriculoarterial discordance and tricuspid atresia.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
从最新的版本中选择一种：
Genetic diversities of MT-ND1 and MT-ND2 genes are associated with high-altitude adaptation in yak.
Shi Y, et al.
Mitochondrial DNA. Part A, DNA mapping, sequencing, and analysis, 29(3), 485-494 (2018)
Mitochondrial ND1 variants in 1281 Chinese subjects with Leber's hereditary optic neuropathy.
Ji Y, et al.
Investigative Ophthalmology & Visual Science, 57(6), 2377-2389 (2016)
Determination of a New Mutation in MT?ND 1 Gene of a Patient With Dextrocardia, Ventriculoarterial Discordance, and Tricuspid Atresia.
Hatemi AC, et al.
Artificial Organs, 39(1), 83-84 (2015)
Engy A Abdel-Rahman et al.
Journal of advanced research, 31, 35-47 (2021-07-02)
Incidents of myocardial infarction and sudden cardiac arrest vary with time of the day, but the mechanism for this effect is not clear. We hypothesized that diurnal changes in the ability of cardiac mitochondria to control calcium homeostasis dictate vulnerability
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