Anti-Histone H2A antibody produced in rabbit

Anti-Histone H2A Antibody detects endogenous levels of total Histone H2A protein.
Histones have an important role in the organization and modification of chromatin. The nucleosome is the basic unit of the chromatin. It is made up of two molecules each of histones H2A, H2B, H3 and H4 wrapped with approximately 146bp of DNA. Histone H1 binds to the nucleosomes at the DNA entry and exit points and stabilizes them. Histone cluster 1 H2A family member I (HIST1H2AI) or H2A/c is a replication-dependent isoform of histone H2A. It stabilizes the histone core octamer and the gene encoding it is localized on human chromosome 6p22.1.

The antiserum was produced against synthesized peptide derived from human Histone H2A.

Immunogen Range: 81-130

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Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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