生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen 85 kDa
种属反应性
human, rat, mouse
浓度
~1 mg/mL
技术
ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... GCR(2908)
一般描述
Anti-GR antibody detects endogenous levels of total GR protein.
Glucocorticoid receptor (GR) gene/NR3C1 (nuclear receptor subfamily 3 group C member 1) is located on human chromosome 5q31.
免疫原
The antiserum was produced against synthesized peptide derived from human GR.
Immunogen Range: 201-250
Immunogen Range: 201-250
应用
Anti-GR antibody has been used in western blotting.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
生化/生理作用
The glucocorticoid receptor (GR) gene/(NR3C1) is associated with asthma. It is required for glucose homeostasis, hyperinsulinemia and increased fat deposition. It also regulates cell differentiation, nervous and immune system functions.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
The Role of Hippocampal NMDA Receptors in Long-Term Emotional Responses following Muscarinic Receptor Activation
Hoeller AA, et al.
PLoS ONE, 11(1), e0147293-e0147293 (2016)
Alexandre A Hoeller et al.
PloS one, 11(1), e0147293-e0147293 (2016-01-23)
Extensive evidence indicates the influence of the cholinergic system on emotional processing. Previous findings provided new insights into the underlying mechanisms of long-term anxiety, showing that rats injected with a single systemic dose of pilocarpine--a muscarinic receptor (mAChR) agonist--displayed persistent
Glucocorticoid receptor polymorphism in obesity and glucose homeostasis
Majer-Lobodzinska A and Adamiec-Mroczek J
Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University, 26(1), 143-148 (2017)
Identification of polymorphisms in the human glucocorticoid receptor gene (NR3C1) in a multi-racial asthma case and control screening panel
Hawkins GA, et al.
Dna Sequence, 15(3), 167-173 (2004)
Structure of the glucocorticoid receptor (NR3C1) gene 5' untranslated region: identification, and tissue distribution of multiple new human exon 1
Turner JD and Muller CP
Journal of Molecular Endocrinology, 35(2), 283-292 (2005)
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