推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 38 kDa
种属反应性
mouse, human, rat
浓度
~1 mg/mL
技术
ELISA: 1:1000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... GPR18(2841)
一般描述
Anti-GPR18 antibody detects endogenous levels of total GPR18 protein. G protein-coupled receptor 18 (GPR18) is made up of 331 amino acids. GPR18 mRNA is located in murine spleen, bone marrow, thymus, lung and cerebellar tissue. This gene is located on human chromosome 13q32.
免疫原
The antiserum was produced against synthesized peptide derived from human GPR18.
Immunogen Range: 191-240
Immunogen Range: 191-240
生化/生理作用
G protein-coupled receptor 18 (GPR18) participates in cell migration and apoptosis. It modulates mitogen-activated protein kinases (MAPK) activity and immune stimulation.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Characterization of non-olfactory GPCRs in human sperm with a focus on GPR18
Flegel C, et al.
Scientific Reports, 6, 32255-32255 (2016)
Junio Dort et al.
Nature communications, 12(1), 6264-6264 (2021-10-31)
Lack of dystrophin causes muscle degeneration, which is exacerbated by chronic inflammation and reduced regenerative capacity of muscle stem cells in Duchenne Muscular Dystrophy (DMD). To date, glucocorticoids remain the gold standard for the treatment of DMD. These drugs are
D McHugh
British journal of pharmacology, 167(8), 1575-1582 (2012-05-09)
A review of what is presently known about the G protein coupled receptor GPR18 in terms of its expression and distribution, pharmacology and potential implications for central nervous system and endocannabinoid system signalling. LINKED ARTICLES This article is part of
Ceren Emre et al.
Communications biology, 5(1), 245-245 (2022-03-23)
Sustained microglial activation and increased pro-inflammatory signalling cause chronic inflammation and neuronal damage in Alzheimer's disease (AD). Resolution of inflammation follows neutralization of pathogens and is a response to limit damage and promote healing, mediated by pro-resolving lipid mediators (LMs).
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