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安全信息

SAB4501054

Sigma-Aldrich

Anti-ZDHHC20 antibody produced in rabbit

affinity isolated antibody

别名:

DHHC-20, Zinc finger DHHC domain-containing protein 20

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

antigen 42 kDa

种属反应性

rat, human, mouse

浓度

~1 mg/mL

技术

ELISA: 1:10000
western blot: 1:500-1:1000

NCBI登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

相关类别

一般描述

Anti-ZDHHC20 Antibody detects endogenous levels of total ZDHHC20 protein.

免疫原

The antiserum was produced against synthesized peptide derived from human ZDHHC20.

Immunogen Range: 72-121

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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Francisco S Mesquita et al.
Nature communications, 14(1), 7302-7302 (2023-11-12)
SARS-CoV-2 infection requires Spike protein-mediated fusion between the viral and cellular membranes. The fusogenic activity of Spike depends on its post-translational lipid modification by host S-acyltransferases, predominantly ZDHHC20. Previous observations indicate that SARS-CoV-2 infection augments the S-acylation of Spike when
Francisco S Mesquita et al.
Developmental cell, 56(20), 2790-2807 (2021-10-03)
SARS-CoV-2 virions are surrounded by a lipid bilayer that contains membrane proteins such as spike, responsible for target-cell binding and virus fusion. We found that during SARS-CoV-2 infection, spike becomes lipid modified, through the sequential action of the S-acyltransferases ZDHHC20

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