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安全信息

SAB4501013

Sigma-Aldrich

Anti-OPN3 antibody produced in rabbit

affinity isolated antibody

别名:

ECPN, Encephalopsin, OPN3, Opsin-3, Panopsin

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

antigen 44 kDa

种属反应性

human, mouse

浓度

~1 mg/mL

技术

ELISA: 1:10000
western blot: 1:500-1:1000

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... OPN3(23596)

一般描述

Anti-OPN3 Antibody detects endogenous levels of total OPN3 protein.
Opsin 3 (OPN3) is also termed as encephalopsin or panopsin. It is a member of the encephalopsin/tmt-opsin subfamily. It is expressed in brain, liver, placenta, heart and pancreatic tissues. The OPN3 gene is located on human chromosome 1q43.

免疫原

The antiserum was produced against synthesized peptide derived from human OPN3.

Immunogen Range: 161-210

生化/生理作用

Opsin3 controls the apoptotic pathway and makes hepatocellular carcinoma cells fragile to 5-fluorouracil treatment. OPN3 plays an important role in oncogenesis and drug resistance. It also plays crucial roles in various physiological and pathological processes.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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储存分类代码

12 - Non Combustible Liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Opsin3 sensitizes hepatocellular carcinoma cells to 5-fluorouracil treatment by regulating the apoptotic pathway.
Jiao J, et al.
Cancer Letters, 320(1), 96-103 (2012)
Curcumin alleviated oxidation stress injury by mediating osteopontin in nephrolithiasis rats.
Huang, et al.
Acta Cirurgica Brasileira / Sociedade Brasileira Para Desenvolvimento Pesquisa em Cirurgia, 38, e380223-e380223 (2023)
Bioinformatic Analysis of Human OPN3 Alternative Promoters Associated with Cancer.
Al-Obaide MA, et al.
Applied Mathematics & Information Sciences, 10, 1223-1229 (2016)
Multiple hits for the association of uterine fibroids on human chromosome 1q43.
Aissani B, et al.
PLoS ONE, 8(3), e58399-e58399 (2013)
Encephalopsin (OPN3) protein abundance in the adult mouse brain.
Nissila J, et al.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 198(11), 833-839 (2012)

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