生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen 34 kDa
种属反应性
human, rat, mouse
浓度
~1 mg/mL
技术
ELISA: 1:1000
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... FCGR2B(2213)
一般描述
The human immune system has six FcγRs-FcγRI, FcγRIIA, FcγRIIB, FcγRIIC, FcγRIIIA and FcγRIIIB. FcγRIIIB/CD32 (Fc fragment of IgG receptor IIb) is an inhibitory receptor that is located on human chromosome 1q23.
Anti-CD32 Antibody detects endogenous levels of total CD32 protein.
Anti-CD32 Antibody detects endogenous levels of total CD32 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human CD32.
Immunogen Range: 277-326
Immunogen Range: 277-326
生化/生理作用
FcγRIIIB/CD32 (Fc fragment of IgG receptor IIb) controls the generation of autoantibodies and their effector roles. During a viral memory response, FcγRIIB blocks the generation of inflammatory type I IFN from plasmacytoid dendritic cells.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Impairment on the lateral mobility induced by structural changes underlies the functional deficiency of the lupus-associated polymorphism Fc?RIIB-T232
The Journal of Experimental Medicine (2016)
Fc?RIIB and autoimmunity
Immunological Reviews (2016)
Fc?RIIB prevents inflammatory type I IFN production from plasmacytoid dendritic cells during a viral memory response
Journal of Immunology (2015)
Association of a transmembrane polymorphism of Fcgamma receptor IIb (FCGR2B) with systemic lupus erythematosus in Taiwanese patients
Arthritis and Rheumatism (2006)
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