生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen 46 kDa
种属反应性
human
浓度
~1 mg/mL
技术
ELISA: 1:40000
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... GDF7(151449)
一般描述
BMPs (bone morphogenetic proteins) belong to the transforming growth factor-β (TGF-β) superfamily of structurally related signaling proteins. BMP-12 is highly conserved across species. The gene encoding this protein is localized on human chromosome 2. Anti-GDF7 Antibody detects endogenous levels of total GDF7 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human GDF7.
Immunogen Range: 191-240
Immunogen Range: 191-240
生化/生理作用
As implied by their name, BMPs (bone morphogenetic proteins) promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP-12 regulates chondrogenesis, bone morphogenesis, and neuron differentiation. It also has a role in seminal vesicle development.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
The Barrett-associated variants at GDF7 and TBX5 also increase esophageal adenocarcinoma risk.
Becker J
Cancer Medicine, 5(5), 888-891 (2016)
The family of bone morphogenetic proteins.
Ducy P and Karsenty G
Kidney International, 57(6), 2207-2214 (2000)
Bone Morphogenetic Protein (BMP) signaling in development and human diseases.
Wang RN
Genes & Development, 1(1), 87-105 (2014)
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