推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 45 kDa
种属反应性
mouse, human, rat
浓度
~1 mg/mL
技术
ELISA: 1:10000
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... CSNK2A1(1457)
一般描述
Anti-Casein Kinase II α Antibody detects endogenous levels of total Casein Kinase II α protein.
Casein kinase II α (CK2) is a pleiotropic serine/threonine kinase, that is located on human chromosome 16p13.2–13.3.
免疫原
The antiserum was produced against synthesized peptide derived from human Casein Kinase II alpha.
Immunogen Range: 221-270
Immunogen Range: 221-270
生化/生理作用
Casein kinase II α(CK2) mutations results in neurodevelopmental abnormalities and dysmorphic features. It regulates T-cell polarization by initiating dendritic cell. CK2 participates in the development of breast carcinoma. It induces prosurvival and proinflammatory signaling pathways.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
De novo mutations in CSNK2A1 are associated with neurodevelopmental abnormalities and dysmorphic features
Okur V, et al.
Human Genetics, 135(7), 699-705 (2016)
Ets1 is a common element in directing transcription of the alpha and beta genes of human protein kinase CK2
Krehan A, et al.
European Journal of Biochemistry, 268(11), 3243-3252 (2001)
Protein kinase CK2 controls T-cell polarization through dendritic cell activation in response to contact sensitizers
de Bourayne M, et al.
Journal of Leukocyte Biology, 101(3), 703-715 (2017)
Protein Kinase CK2 Controls the Fate between Th17 Cell and Regulatory T Cell Differentiation
Gibson SA, et al.
Journal of Immunology, 198(11), 4244-4254 (2017)
CK2?/CSNK2A1 Phosphorylates SIRT6 and Is Involved in the Progression of Breast Carcinoma and Predicts Shorter Survival of Diagnosed Patients
Bae JS, et al.
The American Journal of Pathology, 186(12), 3297-3315 (2016)
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