生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
antigen 160 kDa
种属反应性
human, mouse
浓度
~1 mg/mL
技术
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... COL4A1(1282)
一般描述
抗IV型胶原抗体可检测总内源性IV型胶原蛋白水平。
COL4A1(IV型胶原蛋白α1链)属于胶原蛋白家族。它具有N末端7S结构域、C末端球状结构域(NC1),以及包含Gly-X-Y重复短暂中断的中心三螺旋结构域。它是基底膜IV型胶原的重要成分。COL4A1基因位于人类染色体13q34上。
免疫原
用人IV型胶原合成肽免疫制备抗血清。
免疫原范围: 11-60
免疫原范围: 11-60
应用
IV型胶原N端肽抗体已用于组织学分析、免疫荧光显微镜检查和免疫染色。
生化/生理作用
COL4A1(IV型胶原蛋白α1链)相关疾病与肺部并发症有关。该基因是基膜稳定性所需的主要成分。COL4A1的突变导致家族性脑膜炎、婴儿型偏瘫、脑小血管病(CSVD)和出血性中风。
特点和优势
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用,我们将全额退款或安排替代抗体。了解更多信息。
外形
兔IgG,溶于磷酸盐缓冲液(不含Mg2+和Ca2+),pH 7.4,150mM NaCl,0.02%叠氮化钠和50%甘油中。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
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WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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