产品名称
抗-胶原蛋白IV 兔抗, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 160 kDa
species reactivity
human, mouse
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... COL4A1(1282)
Application
IV型胶原N端肽抗体已用于组织学分析、免疫荧光显微镜检查和免疫染色。
Biochem/physiol Actions
COL4A1(IV型胶原蛋白α1链)相关疾病与肺部并发症有关。该基因是基膜稳定性所需的主要成分。COL4A1的突变导致家族性脑膜炎、婴儿型偏瘫、脑小血管病(CSVD)和出血性中风。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
Features and Benefits
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General description
抗IV型胶原抗体可检测总内源性IV型胶原蛋白水平。
COL4A1(IV型胶原蛋白α1链)属于胶原蛋白家族。它具有N末端7S结构域、C末端球状结构域(NC1),以及包含Gly-X-Y重复短暂中断的中心三螺旋结构域。它是基底膜IV型胶原的重要成分。COL4A1基因位于人类染色体13q34上。
Immunogen
用人IV型胶原合成肽免疫制备抗血清。
免疫原范围: 11-60
免疫原范围: 11-60
Physical form
兔IgG,溶于磷酸盐缓冲液(不含Mg2+和Ca2+),pH 7.4,150mM NaCl,0.02%叠氮化钠和50%甘油中。
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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