产品名称
抗 CD63, affinity isolated antibody
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
species reactivity
human, mouse
technique(s)
immunohistochemistry: 1:25-1:100
western blot: 1:500-1:2000
accession no.
NP_001244318
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CD63(967)
Biochem/physiol Actions
分化簇(CD63)可作为血小板活化标志物。它在细胞增殖、粘附、运动和分化的调节中起重要作用。CD63可作为肺腺癌的预后标志物。CD63缺乏与Hermansky−Pudlak综合征(HPS)相关。
Features and Benefits
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General description
分化簇(CD63)属于四次跨膜蛋白,含有四个跨膜结构域。它位于晚期核内体和溶酶体中。该基因位于人染色体12q13.2上。CD63是一种膜结合糖蛋白。
Immunogen
人 CD63 分子的合成肽
Physical form
兔 IgG 溶于 pH7.4 PBS、0.05%NaN3、40% 甘油中。
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Dongdong Tian et al.
International journal of molecular medicine, 50(1) (2022-05-28)
Chronic obstructive pulmonary disease (COPD) is one of the major causes of death worldwide today, and its related morbidity has been predicted to show an increase in subsequent years. Recent studies have shown that Danshen, a Chinese herbal medicine, is
Hermansky-Pudlak syndrome: a disease of protein trafficking and organelle function
Wei ML
Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 19(1), 19-42 (2006)
Trafficking and function of the tetraspanin CD63
Pols MS and Klumperman J
Experimental Cell Research, 315(9), 1584-1592 (2009)
Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes
De Leeuw RJ, et al.
Human Molecular Genetics, 13(17), 1827-1837 (2004)
Łukasz Zadka et al.
The American journal of pathology, 191(12), 2147-2171 (2021-08-25)
Three-dimensional (3D) imaging and quantitative analysis of extracellular vesicles (EVs) remain largely unexplored, mainly because of limitations in detection techniques. In this study, EVs from patients diagnosed with colorectal cancer (CRC) and ulcerative colitis were examined. To investigate the spatial
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