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安全信息

SAB4301196

Sigma-Aldrich

Anti-CDK19 antibody produced in rabbit

affinity isolated antibody

别名:

CDC2L6, CDK11, bA346C16.3

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

57 kDa

种属反应性

human, mouse

浓度

3 mg/mL

技术

immunohistochemistry: 1:100- 1:300
western blot: 1:500-1:2000 (Cell Lysate)

同位素/亚型

IgG

登记号

NP_001287889.1

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... CDK19(23097)

特异性

The antibody detects endogenous levels of total CDK19 protein.

免疫原

Synthetic peptide corresponding to residues near the N terminal of human cyclin-dependent kinase 19

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Jenny Zhe Liao et al.
Nature communications, 15(1), 3326-3326 (2024-04-19)
Cdk8 in Drosophila is the orthologue of vertebrate CDK8 and CDK19. These proteins have been shown to modulate transcriptional control by RNA polymerase II. We found that neuronal loss of Cdk8 severely reduces fly lifespan and causes bang sensitivity. Remarkably
Sonia Mediouni et al.
mBio, 10(1) (2019-02-07)
The intrinsically disordered HIV-1 Tat protein binds the viral RNA transactivation response structure (TAR), which recruits transcriptional cofactors, amplifying viral mRNA expression. Limited Tat transactivation correlates with HIV-1 latency. Unfortunately, Tat inhibitors are not clinically available. The small molecule didehydro-cortistatin

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