SAB4301171
Anti-MT-CO2 antibody produced in rabbit
affinity isolated antibody
别名:
COII, COXII, MTCO2
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关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
26 kDa
species reactivity
human, mouse
concentration
1 mg/mL
technique(s)
immunohistochemistry: 1:10- 1:50, western blot: 1:500-1:2000 (Cell Lysate)
isotype
IgG
accession no.
P00403
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MT-CO2(4513)
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General description
Mitochondrially encoded cytochrome c oxidase II (MT-CO2) is a key subunit of cytochrome c oxidase, which is the terminal enzyme involved in the oxidative phosphorylation complexes.
Immunogen
Synthetic peptide corresponding to a region derived from internal residues of human mitochondrially encoded cytochrome c oxidase II
Biochem/physiol Actions
Polymorphism in mitochondrially encoded cytochrome c oxidase II (MT-CO2) might alter electron transfer from cytochrome c to the bimetallic center of the catalytic subunit I. Aberrations in MT-CO2 expression has been observed in prostate cancer patients.
The antibody detects endogenous levels of total MT-CO2 protein.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Mitochondrial cytochrome c oxidase subunit II variations predict adverse prognosis in cytogenetically normal acute myeloid leukaemia.
Silkjaer T, et al.
European Journal of Haematology, 91(4), 295-303 (2013)
Altered expression of 12S/MT-RNR1, MT-CO2/COX2, and MT-ATP6 mitochondrial genes in prostate cancer.
Abril J, et al.
Prostate, 68(10), 1086-1096 (2008)
A novel MT-CO2 m.8249G?>?A pathogenic variation and the MT-TW m.5521G?>?A mutation in patients with mitochondrial myopathy
Mkaouar-Rebai E, et al.
Mitochondrial DNA, 25(5), 394-399 (2014)
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