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安全信息

SAB4301129

Sigma-Aldrich

Anti-MYH4 antibody produced in rabbit

affinity isolated antibody

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别名:
MyHC-2b, Myosin heavy chain, Myosin heavy chain 2b, Myosin heavy chain 4, Myosin-4
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

224 kDa

种属反应性

human

浓度

1.0 mg/mL

技术

immunohistochemistry: 1:50-1:100

同位素/亚型

IgG

登记号

NP_060003.2

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... MYH4(4622)

特异性

The antibody detects endogenous levels of total MYH4 protein.

免疫原

Synthesized peptide derived from C-terminal of human MYH4.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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Letter to the editor: Comments on Stuart et al. (2016): "Myosin content of individual human muscle fibers isolated by laser capture microdissection".
Stefano Schiaffino et al.
American journal of physiology. Cell physiology, 311(6), C1048-C1049 (2016-12-14)
Junmei Wang et al.
Scientific reports, 9(1), 3920-3920 (2019-03-10)
Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disease involving motor neuron death, paralysis and, ultimately, respiratory failure. Motor neuron dysfunction leads to target skeletal muscle atrophy involving dysregulation of downstream cell survival, growth and metabolic signaling. Decreased Akt activity
Charles A Stuart et al.
American journal of physiology. Cell physiology, 310(5), C381-C389 (2015-12-18)
Muscle fiber composition correlates with insulin resistance, and exercise training can increase slow-twitch (type I) fibers and, thereby, mitigate diabetes risk. Human skeletal muscle is made up of three distinct fiber types, but muscle contains many more isoforms of myosin

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