生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
mouse, human
浓度
1.3 mg/mL
技术
immunohistochemistry: 1:25- 1:100
同位素/亚型
IgG
登记号
NP_001073922.2
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... INTS1(26173)
特异性
The antibody detects endogenous levels of total INTS1 protein.
免疫原
Synthetic peptide corresponding to residues near the N terminal of human integrator complex subunit 1
应用
Anti-INTS1 antibody produced in rabbit is suitable for immunohistochemistry studies at a dilution of 1:25 - 1:100.
生化/生理作用
INTS1 (Integrator complex subunit 1), a large nuclear protein, involved in the processing of small nuclear RNA as a major component of the Integrator complex. During transcriptional regulation and in RNA processing, it directly binds to the C-terminal domain of the RNA polymerase II largest subunit. It has been reported that INTS1 is also involved in different cell support processes such as the formation of a scaffold for the assembly of integrator complex.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Toshiyuki Hata et al.
Biochimica et biophysica acta, 1773(7), 1039-1051 (2007-06-05)
The KIAA1440 protein contains no significant domains that allow for a prediction of its function, despite the fact that it is an extremely large protein comprising 2222 amino acids. In our current study, we show that the developing KIAA1440(-/-) mouse
David Baillat et al.
Cell, 123(2), 265-276 (2005-10-22)
The C-terminal domain (CTD) of RNA polymerase II (RNAPII) is an essential component of transcriptional regulation and RNA processing of protein-coding genes. A large body of data also implicates the CTD in the transcription and processing of RNAPII-mediated small nuclear
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