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生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
11 kDa
种属反应性
rat, mouse, human
浓度
1.0 mg/mL
技术
immunohistochemistry: 1:50- 1:200
western blot: 1:500-1:2000 (Cell Lysate)
同位素/亚型
IgG
登记号
NP_003539.1
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
dimethylation (Arg3)
基因信息
human ... HIST2H4A(8370)
免疫原
A synthetic peptide corresponding to the amino terminus of histone H4 in which Arg3 is di-methylated.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
法规信息
常规特殊物品
历史批次信息供参考:
Satya K Kota et al.
Bone, 117, 37-46 (2018-09-07)
Protein arginine methyltransferases (PRMTs) catalyze symmetric and asymmetric methylation on arginine residues of multiple protein targets including histones and have essential roles in organismal development and disease. PRMT5 mediates symmetric di-methylation (sDMA) of arginine 2 (H3R2me2s) and arginine 8 on
Zhiwei Zheng et al.
Journal of pharmaceutical analysis, 13(6), 590-602 (2023-07-13)
This study aimed to evaluate the therapeutic potential of inhibiting protein arginine methyltransferase 5 (PRMT5) in cisplatin-induced hearing loss. The effects of PRMT5 inhibition on cisplatin-induced auditory injury were determined using immunohistochemistry, apoptosis assays, and auditory brainstem response. The mechanism
Stephanie A Amici et al.
Frontiers in immunology, 12, 695947-695947 (2021-06-26)
Multiple Sclerosis (MS) is a debilitating central nervous system disorder associated with inflammatory T cells. Activation and expansion of inflammatory T cells is thought to be behind MS relapses and influence disease severity. Protein arginine N-methyltransferase 5 (PRMT5) is a
PRMT5 in T Cells Drives Th17 Responses, Mixed Granulocytic Inflammation, and Severe Allergic Airway Inflammation.
Lewis, et al.
Journal of immunology (Baltimore, Md. : 1950), 208, 1525-1533 (2023)
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