Anti-Fibrillarin antibody produced in rabbit

The antibody detects endogenous level of total Fibrillarin protein.

Peptide sequence around aa. 297-301 ( L-T-L-E-P), according to the protein NP_001427.2

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Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2′-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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