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Merck
CN

SAB4300628

Anti-phospho-CK2α (pThr360/Ser362) antibody produced in rabbit

affinity isolated antibody

别名:

Anti-CK2A1, Anti-CKII, Anti-CSNK2A1

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
human, rat, mouse
Citations:
2
Technique(s):
western blot: 1:500-1:1000
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产品名称

Anti-phospho-CK2α (pThr360/Ser362) antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~42 kDa

species reactivity

human, rat, mouse

concentration

1 mg/mL

technique(s)

western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(V-P-Tp-P-Sp-P-L)

NCBI accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pThr360/pSer362)

Quality Level

Gene Information

human ... CTNNA1(1495)

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

General description

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha′ chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates ′Ser-392′ of p53/TP53 following UV irradiation.
The antibody detects endogenous level of CK2 only when phosphorylated at thronine 360.

Immunogen

Peptide sequence around phosphorylation site of threonine360/serine 362 (V-P-Tp-P-Sp-P-L), according to the protein NP_001894.2

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Feng-Ming Yang et al.
The Journal of clinical investigation, 128(6), 2459-2472 (2018-05-08)
Many Toll-like receptors (TLRs) signal through TNF receptor-associated factor 6 (TRAF6) to activate innate immune responses. Here, we show that somatic nuclear autoantigenic sperm protein (sNASP) binds to TRAF6 to prevent TRAF6 autoubiquitination in unstimulated macrophages. Following LPS stimulation, a
Mitsutoshi Ota et al.
Arthritis & rheumatology (Hoboken, N.J.), 72(6), 931-942 (2019-12-01)
We have previously reported that the coactivation of NF-κB and STAT3 in nonimmune cells, including synovial fibroblasts, enhances the expression of NF-κB target genes and plays a role in chronic inflammation and rheumatoid arthritis (RA). This study was undertaken to

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