SAB4300540
Anti-PRKCQ (Ab-676) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-MGC126514 antibody produced in rabbit, Anti-MGC141919 antibody produced in rabbit, Anti-PRKCT antibody produced in rabbit, Anti-nPKC-theta antibody produced in rabbit, Anti-protein kinase C, theta antibody produced in rabbit
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所有图片(3)
About This Item
UNSPSC代码:
12352203
NACRES:
NA.41
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
分子量
~80 kDa
种属反应性
human
浓度
1 mg/mL
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000
同位素/亚型
IgG
免疫原序列
(R-L-S-F-A)
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... PRKCQ(5588)
免疫原
Peptide sequence around aa. 674-678 (R-L-S-F-A), according to the protein PRKCQ.
特点和优势
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目标描述
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. Ref.8 PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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