SAB4300443
Anti-PRKDC (Ab-2609) antibody produced in rabbit
affinity isolated antibody
别名:
Anti-DNA-PKcs antibody produced in rabbit, Anti-DNAPK antibody produced in rabbit, Anti-DNPK1 antibody produced in rabbit, Anti-HYRC antibody produced in rabbit, Anti-protein kinase, DNA-activated, catalytic polypeptide antibody produced in rabbit
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About This Item
推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
~450 kDa
种属反应性
human
浓度
1 mg/mL
技术
western blot: 1:500-1:1000
同位素/亚型
IgG
免疫原序列
(V-E-T-Q-A)
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... PRKDC(5591)
免疫原
Peptide sequence around aa. 2607-2611 (V-E-T-Q-A), according to the protein PRKDC.
特点和优势
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目标描述
The PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Ekaterina Knyazhanskaya et al.
Retrovirology, 16(1), 30-30 (2019-11-07)
HIV-1 integration results in genomic DNA gaps that are repaired by cellular DNA repair pathways. This step of the lentiviral life cycle remains poorly understood despite its crucial importance for successful replication. We and others reported that Ku70 protein of
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