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主要文件

安全信息

SAB4300434

Sigma-Aldrich

Anti-PAK1/PAK2/PAK3 (Ab-423/402/421) antibody produced in rabbit

affinity isolated antibody

别名:

Anti-CDKN1A antibody produced in rabbit, Anti-MGC130000 antibody produced in rabbit, Anti-PAK65 antibody produced in rabbit, Anti-p21 protein (Cdc42 / Rac)-activated kinase 1 / 2 / 3 antibody produced in rabbit

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

61-67 kDa
68-74 kDa

种属反应性

rat, human, mouse

浓度

1 mg/mL

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200

同位素/亚型

IgG

免疫原序列

(R-S-T-M-V)

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

相关类别

免疫原

Peptide sequence around aa. 421-425/400-404/419-423 (R-S-T-M-V), according to the proteins PAK1/PAK2/PAK3.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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