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安全信息

SAB4300426

Sigma-Aldrich

Anti-NOS1 (Ab-852) antibody produced in rabbit

affinity isolated antibody

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别名:
Anti-IHPS1 antibody produced in rabbit, Anti-NOS antibody produced in rabbit, Anti-nNOS antibody produced in rabbit, Anti-nitric oxide synthase 1 (neuronal) antibody produced in rabbit
MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

~160 kDa

种属反应性

mouse, rat, human

浓度

1 mg/mL

技术

indirect immunofluorescence: 1:100-1:200

同位素/亚型

IgG

免疫原序列

(F-N-S-V-S)

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... NOS1(4842)

一般描述

NOS1 (nitric oxide synthase 1) is one of the NOS (nitric oxide synthase) isoforms found in the heart. It is located on human chromosome 12q24.2-31. It is mainly localized in the sarcoplasmic reticulum (SR).

免疫原

Peptide sequence around aa. 850-854 (F-N-S-V-S), according to the protein NOS1.

应用

Anti-NOS1 (Ab-852) antibody has been used in immunocytochemistry .

生化/生理作用

NOS (nitric oxide synthase) produce nitric oxide in the heart.It regulates myocardial function and plays an important role in the remodeling of human (ICM) ischemic cardiomyopathy.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Converging evidence for an impact of a functional NOS gene variation on anxiety-related processes
Kuhn M, et al.
Social Cognitive and Affective Neuroscience, 11(5), 803-812 (2016)
Ana C Bahia et al.
PLoS neglected tropical diseases, 5(11), e1317-e1317 (2011-11-10)
Malaria affects 300 million people worldwide every year and 450,000 in Brazil. In coastal areas of Brazil, the main malaria vector is Anopheles aquasalis, and Plasmodium vivax is responsible for the majority of malaria cases in the Americas. Insects possess
The JAK-STAT pathway controls Plasmodium vivax load in early stages of Anopheles aquasalis infection
Bahia AC, et al.
PLoS Neglected Tropical Diseases, 5(11) (2011)
Roles of nitric oxide and superoxide in inflammation.
Daniela Salvemini et al.
Methods in molecular biology (Clifton, N.J.), 225, 291-303 (2003-05-29)

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