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安全信息

SAB4300338

Sigma-Aldrich

Anti-NBN (Ab-343) antibody produced in rabbit

affinity isolated antibody

别名:

Anti-AT-V1 antibody produced in rabbit, Anti-AT-V2 antibody produced in rabbit, Anti-ATV antibody produced in rabbit, Anti-FLJ10155 antibody produced in rabbit, Anti-nibrin antibody produced in rabbit

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

分子量

~95 kDa

种属反应性

human

浓度

1 mg/mL

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
western blot: 1:500-1:1000

同位素/亚型

IgG

免疫原序列

(S-L-S-Q-G)

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... NBN(4683)

免疫原

Peptide sequence around aa. 341-345 (S-L-S-Q-G), according to the protein NBN.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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