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安全信息

SAB4300232

Sigma-Aldrich

Anti-phospho-GRIA2 (pSer880) antibody produced in rabbit

affinity isolated antibody

别名:

Anti-GLUR2 antibody produced in rabbit, Anti-GLURB antibody produced in rabbit, Anti-GluR-K2 antibody produced in rabbit, Anti-HBGR2 antibody produced in rabbit, Anti-glutamate receptor, ionotropic, AMPA 2 antibody produced in rabbit

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

~100 kDa

种属反应性

mouse, rat, human

浓度

1 mg/mL

技术

western blot: 1:500-1:1000

同位素/亚型

IgG

免疫原序列

(I-E-SP-V-K)

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

phosphorylation (pSer880)

基因信息

human ... GRIA2(2891)

相关类别

免疫原

Peptide sequence around phosphorylation site of serine 880 (I-E-S(p)-V-K), according to the protein GRIA2.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Mahima Sharma et al.
Cerebral cortex (New York, N.Y. : 1991), 29(7), 2932-2946 (2018-07-10)
Metabotropic glutamate receptor-dependent long-term depression (mGluR-LTD) is conventionally considered to be solely dependent on local protein synthesis. Given the impact of epigenetics on memory, the intriguing question is whether epigenetic regulation influences mGluR-LTD as well. G9a/GLP histone lysine methyltransferase complex

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