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Merck
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安全信息

SAB3701278

Sigma-Aldrich

Anti-Human IgG (Fc specific)-Biotin antibody produced in rabbit

affinity isolated antibody, lyophilized powder

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.46

生物来源

rabbit

质量水平

偶联物

biotin conjugate

抗体形式

affinity isolated antibody

抗体产品类型

secondary antibodies

克隆

polyclonal

形式

lyophilized powder

种属反应性

human

技术

ELISA: suitable
immunohistochemistry: suitable
western blot: suitable

运输

wet ice

储存温度

2-8°C

靶向翻译后修饰

unmodified

相关类别

一般描述

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein and mainly helps in immune defense. IgG is usually found as a monomer. IgG is further subdivided into four classes namely, IgG1, IgG2, IgG3, and IgG4. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. About 70% of the total immunoglobulin consists of IgG. Immunoglobulin G (IgG) participates in hypersensitivity type II and type III.

特异性

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Human IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Biotin, Anti-Rabbit Serum, Human IgG, Human IgG F(c) and Human Serum. No reaction was observed against Human IgG F(ab′)2.

免疫原

Human IgG F(c) fragment

物理属性

Antibody format: IgG

外形

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free

重悬

Reconstitute with 1.0 mL deionized water (or equivalent).

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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象形图

Skull and crossbonesEnvironment

警示用语:

Danger

危险声明

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2

补充剂危害

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Lucas A Horn et al.
The Journal of clinical investigation, 132(8) (2022-03-02)
Collagens in the extracellular matrix (ECM) provide a physical barrier to tumor immune infiltration, while also acting as a ligand for immune inhibitory receptors. Transforming growth factor-β (TGF-β) is a key contributor to shaping the ECM by stimulating the production
Specific IgG for cat allergens in patients with allergic conjunctivitis.
Miyama A, et al.
Journal of Ophthalmology, 35(4), 575-586 (2015)
Antibody structure, instability, and formulation.
Wang W
Journal of Pharmaceutical Sciences, 96(1), 1-26 (2007)

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