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Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
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主要文件

安全信息

SAB3700546

Sigma-Aldrich

Anti-Rat IgG (Fc specific) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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选择尺寸

20 μG
¥3,096.05
50 μG
¥5,521.27

¥3,096.05


预计发货时间2025年7月17日详情



选择尺寸

变更视图
20 μG
¥3,096.05
50 μG
¥5,521.27

About This Item

UNSPSC代码:
12352203
NACRES:
NA.46

¥3,096.05


预计发货时间2025年7月17日详情


生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

secondary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

rat

浓度

2.0 mg/mL

技术

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

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此商品
HS120479Z675997BR26311
manufacturer/tradename

Heathrow Scientific HS3000

manufacturer/tradename

Heathrow Scientific HS120479

manufacturer/tradename

Heathrow Scientific HS1000RFU

manufacturer/tradename

BRAND 26311

volume

1-100 mL

volume

1-100 mL

volume

1-100 mL

volume

0.1-200 mL

material

plastic

material

-

material

plastic body, silicone bulb

material

-

一般描述

IgG contributes to 10−20% of plasma protein and is regarded as one of the most predominant serum protein. It consists of four subclasses: IgG1, IgG2, IgG3 and IgG4. The IgG structure possesses four polypeptide chains containing two identical γ heavy (H) chains and two identical κ or λ light (L) chains of 50kDa and 25kDa respectively. Papain and pepsin digestion yields two main fragments of the antibody: Fab (antigen binding fragment) and Fc (fragment crystallization tail).

特异性

This product was prepared from monospecific antiserum by immunoaffinity chromatography using Rat IgG coupled to agarose beads followed by solid phase adsorption(s) to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against Anti-Rabbit Serum, Rat IgG, Rat IgG F(c) and Rat Serum. No reaction was observed against Rat IgG F(ab′)2.

免疫原

Rat IgG F(c) fragment

生化/生理作用

IgG (immunoglobulin G) antibody provides protection against bacterial, fungal and viral infections. Maternal IgG is transferred to fetus through the placenta that is vital for the immune defense of the neonate against infections. The Fc (fragment crystallization tail) region of the antibody is implicated in complement activation in which it elicits an immune response by binding to the Fc receptor on macrophages.

物理属性

Antibody format: IgG

外形

Supplied in 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

  • 历史批次信息供参考:

    分析证书(COA)

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    访问文档库

    Role of antibodies in cancer targeting
    Attarwala Husain
    Journal of natural science, biology, and medicine, 1(1), 53-53 (2010)
    Seon Pyo Hong et al.
    Nature communications, 11(1), 4102-4102 (2020-08-17)
    Emerging evidence suggests that intestinal stromal cells (IntSCs) play essential roles in maintaining intestinal homeostasis. However, the extent of heterogeneity within the villi stromal compartment and how IntSCs regulate the structure and function of specialized intestinal lymphatic capillary called lacteal
    Structure and function of immunoglobulins.
    Schroeder Jr H W and Cavacini L
    The Journal of Allergy and Clinical Immunology, 125(2), S41-S52 (2010)
    Gestur Vidarsson et al.
    Frontiers in immunology, 5, 520-520 (2014-11-05)
    Of the five immunoglobulin isotypes, immunoglobulin G (IgG) is most abundant in human serum. The four subclasses, IgG1, IgG2, IgG3, and IgG4, which are highly conserved, differ in their constant region, particularly in their hinges and upper CH2 domains. These

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