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生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
mouse, human
技术
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... SLC39A6(25800)
一般描述
ZIP6 is encoded by SLC39A6 (solute carrier family 39 member 6) gene. The gene has ten exons and 20864 bases. It is a multi-pass membrane protein and has a molecular weight of 85 kDa. ZIP6 is expressed at high levels in normal breast tissue, prostate, placenta, kidney, pituitary and corpus callosum. This gene is located on human chromosome 18q12.2.
免疫原
ZIP6 antibody was raised against a 16 amino acid peptide near the center of human ZIP6.
生化/生理作用
ZIP6 (ZIP metal ion transporter family) controls the expression level of E-cadherin. It serves as a zinc influx transporter. SLC39A6 participates in the cellular invasion of HeLa cells by modulating the snail and slug expression mediated by ERK (extracellular signal–regulated kinase).
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
联系
The action of this antibody can be blocked using blocking peptide SBP3500597.
外形
Supplied in PBS with 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
SLC39A6 (solute carrier family 39 (zinc transporter), member 6)
Hamada S, et al.
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2011)
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