SAB3500438
Anti-CLDN1 antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
别名:
Anti-CLD1, Anti-CLDN1, Anti-Claudin 1, Anti-ILVASC, Anti-SEMP1
产品名称
Anti-CLDN1 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
rat, mouse, human
technique(s)
immunocytochemistry: suitable
immunofluorescence: suitable
indirect ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CLDN1(9076)
Biochem/physiol Actions
Claudin 1 (CLDN1) has a role in epithelial-mesenchymal transition. It is a sealing and tightening junctional protein. CLDN1 has been shown to be downregulated in lung adenocarcinoma. Mutations in this gene have also been linked to neonatal ichthyosis and sclerosing cholangitis.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Claudin 1 (CLDN1) is a component of tight junctions. It is part of the transmembrane tight junction protein family. The CLDN1 gene is localized on human chromosome 3q28.
Immunogen
CLDN1 antibody was raised against a 20 amino acid peptide near the carboxyl terminus of human CLDN1.
Other Notes
The action of this antibody can be blocked using blocking peptide SBP3500438.
Physical form
Supplied in PBS with 0.02% sodium azide.
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
The impact of CLAUDIN-1 on follicular thyroid carcinoma aggressiveness.
Endocrine-Related Cancer, 22(5) (2015)
Claudin-1 correlates with poor prognosis in lung adenocarcinoma.
Sun BS
Thoracic cancer, 7(5) (2016)
CLDN-1 promoted the epithelial to migration and mesenchymal transition (EMT) in human bronchial epithelial cells via Notch pathway.
Lv J
Molecular and Cellular Biochemistry (2017)
Claudin-1 involved in neonatal ichthyosis sclerosing cholangitis syndrome regulates hepatic paracellular permeability.
Grosse B
Hepatology (2012)
The claudins
Madhu Lal-Nag and Patrice J Morin
Genome Biology (2009)
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