一般描述
β-Galactosidase is coded by the LacZ gene, which helps to transform lactose into galactose. β-Galactosidases are used to produce galactooligosaccharides (GOS). Lactobacillus β-galactosidases are heterodimeric proteins, that are coded by lacL and lacM genes.
β-galactosidase is a tetramer made up of identical four polypeptide chains with a molecular weight of 135,000 each and constituting 1023 amino acids. It is very specific for D-galactose and requires K+ or Na+ and Mg2+ to be fully active. It cleaves lactose into its monosaccharide components, glucose and galactose. The sulfhydryl containing enzyme also catalyzes the transglycosylation of glucose into allolactose, the inducer of β-galactosidase, in a feedback loop.
免疫原
beta-gal antibody was raised against a 17 amino acid peptide from near the amino terminus of E. coliβ-gal.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
联系
The action of this antibody can be blocked using blocking peptide SBP3500043.
外形
Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Structural comparisons of TIM barrel proteins suggest functional and evolutionary relationships between beta-galactosidase and other glycohydrolases
D H Juers
Protein Science (1999)
Characterization of Sulfolobus solfataricus β?galactosidase mutant F441Y expressed in Pichia pastoris.
Sun X, et al.
Journal of the Science of Food and Agriculture, 94(7), 1359-1365 (2014)
LacZ ?-galactosidase: structure and function of an enzyme of historical and molecular biological importance
Protein Science (2012)
PURIFICATION, COMPOSITION, AND MOLECULAR WEIGHT OF THE BETA-GALACTOSIDASE OF ESCHERICHIA COLI K12
G R CRAVEN
The Journal of Biological Chemistry, 240 (1965)
Tian-Kun Hui et al.
Biology, 10(6) (2021-06-03)
Low-density lipoprotein receptor-related protein 4 (Lrp4) is a critical protein involved in the Agrin-Lrp4-MuSK signaling pathway that drives the clustering of acetylcholine receptors (AChRs) at the neuromuscular junction (NMJ). Many studies have shown that Lrp4 also functions in kidney development
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