生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
GT643, monoclonal
形式
buffered aqueous solution
分子量
51-60kDa
种属反应性
Dengue virus
浓度
1mg/mL
技术
flow cytometry: suitable
immunofluorescence: 1:100-1:2,000
western blot: 1:500-1:3,000
同位素/亚型
IgG2b
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
相关类别
一般描述
Dengue virus is an arthropod borne flavivirus. Dengue virus (DENV) is a human pathogen, known to cause one of the major illness, dengue fever (DF) in humans. DENV belongs to the Flaviviridae family. The virus attaches and enters the host cell with the help of a major envelope protein glycoprotein, E. The dengue envelope protein sequence consists of two putative glycosaminoglycan-binding motifs at the carboxy terminus.
免疫原
Recombinant protein encompassing a sequence within the center region of Dengue virus Envelope protein.
应用
Suggested starting dilutions are as follows: ICC/IF: 1:100-1:2000, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
其他说明
Purification: Affinity purified by Protein G
外形
Phosphate-buffered saline, no preservative added.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Type-and subcomplex-specific neutralizing antibodies against domain III of dengue virus type 2 envelope protein recognize adjacent epitopes.
Sukupolvi-Petty S, et al.
Journal of Virology, 81(23), 12816-12826 (2007)
Ankit Kumar et al.
Asian journal of transfusion science, 16(1), 67-72 (2022-10-07)
The study objective was evaluation of amotosalen and ultraviolet A (UVA) illumination-based inactivation of dengue virus (DENV) in blood platelets. Whole blood was collected from healthy donors and platelet concentrates were prepared at a tertiary care hospital in Gurugram, India.
Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate.
Chen Y, et al.
Nature Medicine, 3(8), 866-866 (1997)
A ligand-binding pocket in the dengue virus envelope glycoprotein.
Modis Y, et al.
Proceedings of the National Academy of Sciences of the USA, 100(12), 6986-6991 (2003)
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