Anti-ERCC3 antibody produced in rabbit

Peptide corresponding to the carboxy-terminus of human XPB.

For WB: Use at a dilution of 1:500 and incubate at RT for 40 minutes. Blocking solution: 3% Milk/TBST at RT for one hour. Optimal dilutions/concentrations should be determined by the researcher.

The human XPB DNA helicase is a subunit of the DNA repair/basal transcription factor TFIIH, and is involved in early steps of the nucleotide excision repair (NER) pathway. Two distinct clinical phenotypes, xeroderma pigmentosum associated with Cockayne′s syndrome (XP/CS) and trichothiodystrophy (TTD), can be due to mutations in the XPB gene.

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Phosphate-buffered saline, pH 7.2, containing no preservatives

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