生物来源
mouse
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
5E10
monoclonal
形式
liquid
分子量
84 kDa
种属反应性
mouse, hamster, monkey, rat, human
浓度
1 mg/mL
技术
ChIP: suitable
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG2b
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... THOC1(9984)
免疫原
Amino acids 15-374 of human p84 expressed in E. coli.
应用
Recommended Starting Dilutions: For ICC/IF: Use at a concentration of 0.5 - 2 μg/mL. For IP: 1:100-1:500. For WB: Use at a concentration of 0.3 - 2 μg/mL. For ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher.
生化/生理作用
P84/N5-5E10 recognizes an 84 kDa nuclear matrix protein. Initially isolated by its interaction with the amino terminal region of the retinoblastoma protein, it has been used extensively as a nuclear-specific marker in both immunofluorescence and cell fractionation studies.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Phosphate-buffered saline, no preservative added.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Luping Zhang et al.
PLoS genetics, 16(8), e1008953-e1008953 (2020-08-11)
Apoptosis of cochlear hair cells is a key step towards age-related hearing loss. Although numerous genes have been implicated in the genetic causes of late-onset, progressive hearing loss, few show direct links to the proapoptotic process. By genome-wide linkage analysis
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