推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
polyclonal
形式
liquid
分子量
93 kDa
种属反应性
mouse, bovine, human, rat
浓度
1 mg/mL
技术
ChIP: suitable
immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: 1:100-1:1000
immunoprecipitation (IP): suitable
western blot: 500-10000
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... HIF1A(3091)
免疫原
包含与 HIF1 alpha 的 657 和 826 位氨基酸相对应的序列的重组片段
应用
建议的起始稀释度如下:ICC/IF:1:100-1:1000,IHC-Fr:稀释度由测定方法确定,IHC-P:1:100-1:1000,IP:1:100-1:570, WB:1:500-1:10000,ChIP 测定法:稀释度由测定方法确定。尚未在其他应用中进行测试。最佳工作稀释液应由终端用户通过实验确定。
生化/生理作用
缺氧诱导因子-1 (HIF1)是在低氧培养的哺乳动物细胞中发现的一种转录因子,它在对缺氧的细胞和系统体内稳态反应中起着至关重要的作用。HIF1 是由 α 亚基和 β 亚基组成的异二聚体。β 亚基已被确定为芳香烃受体核转位子(ARNT)。该基因编码 HIF-1 的 α 亚基。研究表明,该基因的天然反义转录物(aHIF)的过表达与非乳头状肾癌有关。已经鉴定出编码不同同工型的两个替代转录本。[由 RefSeq 提供]
特点和优势
您可完全放心的评估我们的抗体。如果抗体在您的应用中没有发挥效果,我们将给予您完全的赔偿或更换抗体。 了解更多。
外形
1XPBS,1%BSA,20% 甘油(pH 7),添加 0.025% 的 ProClin 300 作为防腐剂。
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
警示用语:
Warning
危险声明
危险分类
Aquatic Chronic 3 - Skin Sens. 1
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
含少量动物源组分生物产品
常规特殊物品
Virologica Sinica, 36(6), 1532-1542 (2021-09-15)
Viruses depend on host cellular metabolism to provide the energy and biosynthetic building blocks required for their replication. In this study, we observed that influenza A virus (H1N1), a single-stranded, negative-sense RNA virus with an eight-segmented genome, enhanced glycolysis both
NAR cancer, 2(2), zcaa010-zcaa010 (2020-08-04)
Mechanistic understanding of hypoxia-responsive signaling pathways provides important insights into oxygen- and metabolism-dependent cellular phenotypes in diseases. Using SILAC-based quantitative proteomics, we provided a quantitative map identifying over 6300 protein groups in response to hypoxia in prostate cancer cells and
Cardiovascular research, 104(2), 303-314 (2014-09-23)
Inhibiting angiogenesis is a major approach in tumour therapy. To combat angiogenesis, the tubulin cytoskeleton has emerged as an interesting target in many pre- and clinical studies. Contrarily, the actin cytoskeleton has been largely neglected as a potential drug target
Molecular therapy. Nucleic acids, 20, 292-307 (2020-03-22)
Recently, the identification of several circular RNAs (circRNAs) as vital regulators of microRNAs (miRNAs) underlines the increasing complexity of non-coding RNA (ncRNA)-mediated regulatory networks. This study aimed to explore the effects of mmu_circ_0000790 on the biological behaviors of pulmonary artery
American journal of physiology. Renal physiology, 307(9), F1023-F1032 (2014-07-06)
Podocytes play a key role in the formation of cellular crescents in experimental and human diseases. However, the underlying mechanisms for podocytes in promoting crescent formation need further investigation. Here, we demonstrated that mammalian target of rapamycin complex 1 (mTORC1)
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门