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安全信息

SAB2700682

Sigma-Aldrich

Anti-TET3 (C-terminal) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

别名:

KIAA0401, MGC22014, TET3

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

种属反应性

Xenopus, human, bovine, mouse

技术

ChIP: suitable
immunofluorescence: suitable
immunohistochemistry: 1:100-1:1000
immunoprecipitation (IP): suitable
western blot: 1000-10000

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

基因信息

human ... TET3(200424)

免疫原

Recombinant fragment corresponding to a region within amino acids 1456 and 1660 of TET3 according to AAH22243

应用

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 1:100-1:1000, IP: 1:500-1:1000, WB: 1:1000-1:10000, IHC-Wm: Assay-dependent dilution, ChIP assay: Assay-dependent dilution. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

生化/生理作用

Members of the ten-eleven translocation (TET) gene family, including TET3, play a role in the DNA methylation process (Langemeijer et al., 2009 [PubMed 19923888]).[supplied by OMIM]

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Warning

危险声明

危险分类

Aquatic Chronic 3 - Skin Sens. 1

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Sahar Olsadat Sajadian et al.
Clinical epigenetics, 8, 46-46 (2016-05-03)
5-Azacytidine (5-AZA), a DNA methyl transferase inhibitor, is a clinically used epigenetic drug for cancer therapy. Recently, we have shown that 5-AZA upregulates ten-eleven translocation (TET) protein expression in hepatocellular carcinoma (HCC) cells, which induce active demethylation. Vitamin C facilitates

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