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安全信息

SAB2501960

Sigma-Aldrich

Anti-SLC26A6 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

别名:

DKFZp586E1422, anion transporter 1, pendrin L1, pendrin-like protein 1, solute carrier family 26, member 6

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

goat

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

mouse, pig, human, rat

技术

indirect ELISA: suitable
western blot: suitable

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... SLC26A6(65010)

一般描述

Solute-linked carrier 26 member 6 anion transporter (SLC26A6) belongs to the solute carrier 26 gene family. It codes for an integral membrane protein, that has 10 or 12 transmembrane helices and intracellular amino and carboxy termininal. SLC26A6 is highly expressed in kidney and pancreas. This gene is located on human chromosome 3p21.

免疫原

Peptide with sequence C-RDVAEYSEAKEVR, from the internal region of the protein sequence according to NP_075062.2; NP_599025.2; NP_602298.2; NP_001035544.1

生化/生理作用

Solute-linked carrier 26 member 6 anion transporter (SLC26A6), a multifunctional anion transporter plays a major role in the transport of oxalate anions. Aberrations in the SLC26A6 gene is linked with the threat of kidney stones.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Isoforms of SLC26A6 mediate anion transport and have functional PDZ interaction domains
Lohi H, et al.
American Journal of Physiology. Cell Physiology, 284(3), C769-C779 (2003)
Cloning and characterization of SLC26A6, a novel member of the solute carrier 26 gene family
Waldegger S, et al.
Genomics, 72(1), 43-50 (2001)
Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger
Lohi H, et al.
Genomics, 70(1), 102-112 (2000)
In silico screening and molecular dynamic study of nonsynonymous single nucleotide polymorphisms associated with kidney stones in the SLC26A6 gene
Xiuli L, et al.
The Journal of Urology, 196(1), 118-123 (2016)

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