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安全信息

SAB2501893

Sigma-Aldrich

Anti-SYNGAP1 (N-terminal) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

别名:

DKFZp761G1421, KIAA1938, MRD5, synaptic Ras GTPase activating protein 1

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

goat

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

bovine, rat, canine, pig, mouse, human

技术

indirect ELISA: suitable
western blot: suitable

UniProt登记号

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... SYNGAP1(8831)

免疫原

Peptide with sequence DEDEIHPLLIRDR-C, from the N-terminal region of the protein sequence according toNP_006763.2

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

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分析证书(COA)

Lot/Batch Number

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访问文档库

Yudong Gao et al.
Nature communications, 15(1), 6801-6801 (2024-08-10)
One of the main drivers of autism spectrum disorder is risk alleles within hundreds of genes, which may interact within shared but unknown protein complexes. Here we develop a scalable genome-editing-mediated approach to target 14 high-confidence autism risk genes within
Yoichi Araki et al.
Proceedings of the National Academy of Sciences of the United States of America, 120(37), e2308891120-e2308891120 (2023-09-05)
SYNGAP1 is a Ras-GTPase-activating protein highly enriched at excitatory synapses in the brain. De novo loss-of-function mutations in SYNGAP1 are a major cause of genetically defined neurodevelopmental disorders (NDDs). These mutations are highly penetrant and cause SYNGAP1-related intellectual disability (SRID)

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