SAB2501651
Anti-CREB3L1 (C-terminal) antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
BBF-2 (Drosophila) homolog, CAMP responsive element binding protein 3-like 1, Old astrocyte specifically induced substance
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About This Item
UNSPSC代码:
12352203
NACRES:
NA.41
生物来源
goat
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
种属反应性
human
技术
indirect ELISA: suitable
western blot: suitable
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... CREB3L1(90993)
一般描述
Cyclic AMP-responsive element-binding protein 3-like protein 1 (CREB3L1) belongs to the CREB family of transcription factors. It has a bZIP (basic-leucine zipper) domain and a DNA binding domain. The gene encoding this protein is mapped to human chromosome 11 and is expressed in many tissues.
免疫原
Peptide with sequence DFSHSKEWFHDRD, from the C-terminal region of the protein sequence according to NP_443086.1
生化/生理作用
Cyclic AMP-responsive element-binding protein 3-like protein 1 (CREB3L1) is an unfolded protein response (UPR) transducer. It localizes in the endoplasmic reticulum. In the presence of UPR signaling, CREB3L1 is cleaved and the amino terminal part is translocated to the nucleus. The nuclear part regulates target gene expression. CREB3L1 is involved in the differentiation and development of astrocytes, osteoblasts, odontoblasts, pancreatic beta-cells and large intestine goblet cells.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
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WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
cAMP-Response Element-Binding 3-Like Protein 1 (CREB3L1) is Required for Decidualization and its Expression is Decreased in Women with Endometriosis.
Ahn JI
Current Molecular Medicine (2016)
Epigenetic silencing of CREB3L1 by DNA methylation is associated with high-grade metastatic breast cancers with poor prognosis and is prevalent in triple negative breast cancers.
Ward AK
Breast Cancer Research (2016)
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