SAB2501301
Anti-IDO2 (C-terminal) antibody produced in goat
affinity isolated antibody, buffered aqueous solution
别名:
Anti-INDOL1, indoleamine 2,3-dioxygenase 2
产品名称
Anti-IDO2 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution
biological source
goat
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
canine, bovine, human
technique(s)
indirect ELISA: suitable
western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... IDO2(169355)
Biochem/physiol Actions
Indoleamine 2,3 dioxygenase (IDO) 2 plays an important role in the metabolism of tryptophan and in immune regulation. It may participate in B cell-mediated autoimmune diseases. IDO2 is required for IDO1-dependent induction of T regulatory cells (Treg). Removal of IDO2 results in attenuated contact hypersensitivity (CHS) responses.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
General description
Indoleamine 2,3 dioxygenase (IDO) 2 is one of the four tryptophan catabolic enzymes in mammals. IDO2 is located on human chromosome 8p21.
Immunogen
Peptide with sequence CRDKTLESILHPR, from the C-Terminus of the protein sequence according to NP_919270.2.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
Indoleamine-2, 3-dioxygenase (IDO) 2 polymorphisms are not associated with multiple sclerosis in Italians
C Agliardi, et al.
Journal of the Neurological Sciences, 377, 31-34 (2017)
Richard Metz et al.
International immunology, 26(7), 357-367 (2014-01-10)
IDO2 is implicated in tryptophan catabolism and immunity but its physiological functions are not well established. Here we report the characterization of mice genetically deficient in IDO2, which develop normally but exhibit defects in IDO-mediated T-cell regulation and inflammatory responses.
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