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安全信息

SAB2501133

Sigma-Aldrich

Anti-FEM1A (C-terminal) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

别名:

Anti-DKFZp762M136, Anti-EPRAP, fem-1 homolog a (C. elegans)

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

goat

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

human, bovine, canine

技术

indirect ELISA: suitable
western blot: suitable

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... FEM1A(55527)

一般描述

Fem-1 homolog A (FEM1A) is a homolog of the Fem-1 gene of Caenorhabditis elegans. It is predicted to encode an ankyrin repeat proteins which is expressed in many tissues. FEM1A is a conserved VHL-box protein. The gene encoding it is localized on human chromosome 19p13.3.

免疫原

Peptide with sequence CGFIPEDLEAFIELH, from the C Terminus of the protein sequence according to NP_061178.1.

生化/生理作用

Fem-1 homolog A (FEM1A) is a substrate recognition subunit of cullin-2-RING E3 ubiquitin ligase complex. It has a role in the degradation of stem-loop binding protein (SLBP) and may be involved in anti-inflammatory signaling. FEM1A has been associated with polycystic ovary syndrome.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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访问文档库

FEM1 proteins are ancient regulators of SLBP degradation.
Dankert JF
Cell Cycle (2017)
FEM1A and FEM1B: novel candidate genes for polycystic ovary syndrome.
Goodarzi MO
Human Reproduction (2008)
The Fem1c genes: conserved members of the Fem1 gene family in vertebrates.
Ventura-Holman
Gene (2003)

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