推荐产品
生物来源
goat
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
种属反应性
mouse, rat
技术
immunofluorescence: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... UCP2(7351)
一般描述
Uncoupling protein 2 (UCP2) is an inner mitochondrial membrane protein. It expressed in various regions of the brain. In non-human primates, it is present in the hypothalamic nuclei, pituitary gland, brainstem, ventral tegmental area and substantia nigra. It is located on human chromosome 11q13.
免疫原
Peptide with sequence C-DSVKQFYTKGSEH from the internal region of the protein sequence according to NP_003346.2.
应用
Anti-uncoupling protein 2/UCP2 antibody has been used in immunoblotting.
生化/生理作用
Uncoupling protein 2 (UCP2) controls energy metabolism and decreases the production of reactive oxygen species and guards against reperfusion damage. It plays a vital role in uncoupling electron transport from adenosine triphosphate (ATP) formation.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
含少量动物源组分生物产品
Uncoupling protein 2 haplotype does not affect human brain structure and function in a sample of community-dwelling older adults
Heise, et al.
PLoS ONE, 12(8), e0181392-e0181392 (2017)
The UCP2-866G/A Polymorphism Could be Considered as a Genetic Marker of Different Functional Prognosis in Ischemic Stroke After Recanalization
Cicuendez I D M, et al.
Neuromolecular Medicine, 19(4), 571-578 (2017)
Uncoupling protein 2 region on chromosome 11q13 is not linked to markers of obesity in familial type 2 diabetes
Elbein S C, et al.
Diabetes, 46(12), 2105-2108 (1997)
Jelena Stevanović-Silva et al.
Metabolism: clinical and experimental, 116, 154704-154704 (2021-01-10)
Maternal high-caloric nutrition and related gestational diabetes mellitus (GDM) are associated with a high-risk for developing metabolic complications later in life and in their offspring. In contrast, exercise is recognized as a non-pharmacological strategy against metabolic dysfunctions associated to lifestyle
Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto (mito) phagy markers
Marques A I, et al.
Neuroscience, 301(8), 480-495 (2015)
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