生物来源
goat
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
种属反应性
mouse, human
技术
ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... IFT88(8100)
一般描述
Intraflagellar transport 88 (IFT88) is a liver tumor suppressor gene. It consists of 824 amino acids and possesses tetratricopeptide repeats.
免疫原
Peptide with sequence C-KKRIDEDDFADEE from the C Terminus of the protein sequence according to NP_783195.2; NP_006522.2.
生化/生理作用
Intraflagellar transport 88 (IFT88) is involved in cilia formation. It is linked to polycystic kidney disease. In mitosis, the protein has a crucial role in spindle orientation. IFT88 is downregulated in hepatocellular carcinoma.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
含少量动物源组分生物产品
Tg737 signaling is required for hypoxia-enhanced invasion and migration of hepatoma cells.
You N
Journal of Experimental & Clinical Cancer Research (2012)
Polaris, a Protein Involved in Left-Right Axis Patterning, Localizes to Basal Bodies and Cilia
Patrick D
Molecular Biology of the Cell (2001)
The molecular biology of polycystic kidney disease
Noel S
Pediatric Nephrology (Berlin) (1998)
The cilia protein IFT88 is required for spindle orientation in mitosis.
Delaval B
Nature Cell Biology (2011)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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