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生物来源
goat
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
canine, human, rat, mouse
技术
ELISA: suitable
flow cytometry: suitable
immunohistochemistry: suitable
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... DGAT2(84649)
一般描述
Diacylglycerol O-acyltransferase 2 (DGAT2) possesses one or two transmembrane domains and the amino- and carboxyl-terminal regions face the cytosol. The gene encoding it is localized on human chromosome 11q13.5 and has eight exons.
免疫原
Peptide with sequence C-KLEHPTQQDIDLYH from the internal region (near the C Terminus) of the protein sequence according to NP_115953.2.
生化/生理作用
Diacylglycerol O-acyltransferase 2 (DGAT2) is involved in the final step of triacylglycerol biosynthesis. It esterifies diacylglycerol to triacylglycerol. Overexpression of the protein has been associated with hepatic steatosis.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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警示用语：
Warning
危险声明
预防措施声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Liver fat reduction with niacin is influenced by DGAT-2 polymorphisms in hypertriglyceridemic patients.
Hu M
Journal of Lipid Research (2012)
Expressional profiling of prostate cancer risk SNPs at 11q13.5 identifies DGAT2 as a new target gene.
Nurminen R
Genes Chromosomes Cancer (2016)
Roles of Acyl-CoA:Diacylglycerol Acyltransferases 1 and 2 in Triacylglycerol Synthesis and Secretion in Primary Hepatocytes.
Li C
Arteriosclerosis, Thrombosis, and Vascular Biology (2015)
Justin Chun et al.
Journal of the American Society of Nephrology : JASN, 33(5), 889-907 (2022-03-03)
Two variants in the gene encoding apolipoprotein L1 (APOL1) that are highly associated with African ancestry are major contributors to the large racial disparity in rates of human kidney disease. We previously demonstrated that recruitment of APOL1 risk variants G1
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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