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生物来源
goat
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
human
技术
immunohistochemistry: suitable
indirect ELISA: suitable
indirect immunofluorescence: suitable
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... CRHR1(1394)
一般描述
Corticotropin releasing factor receptor 1 (CRHR1) belongs to the G-protein-coupled receptor superfamily of brain-gut neuropeptides. It is highly expressed in the amygdala, hippocampus and frontal cortex. The gene encoding CRHR1 consists of 13 exons and is localized on human chromosome 17q12-q22.
免疫原
Peptide with sequence KLYYDNEKCWFGKR from the internal region of the protein sequence according to NP_004373.2.
生化/生理作用
Corticotropin releasing factor receptor 1 (CRHR1) helps to initiate signal transduction pathways that control various functions like stress, reproduction, immune response and obesity. It blocks the multiplication of endocrine-related cancer cell lines.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Warning
危险声明
预防措施声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
The activation of type 1 corticotropin releasing factor receptor (CRF-R1) inhibits proliferation and promotes differentiation of neuroblastoma cells in vitro via p27(Kip1) protein up-regulation and c-Myc mRNA down-regulation.
Pozzoli G
Molecular and Cellular Endocrinology (2015)
Association analysis of polymorphisms of the CRHR1 gene with infantile spasms
Guang Yang
Molecular Medicine Reports (2015)
Urocortinergic system in the testes of normal and cryptorchid dogs
Caterina Squillacioti
Annals of Anatomy = Anatomischer Anzeiger : Official Organ of the Anatomische Gesellschaft, 207 (2016)
Family Economic Hardship, Corticotropin-Releasing Hormone Receptor Polymorphisms, and Depressive Symptoms in Rural African American Youths
Yi-fu Chen
The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine (2015)
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