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描述
non-ionic
质量水平
组成
Sapogenin content, ≥10%
技术
HPLC: suitable
protein quantification: suitable
硫酸盐灰分
<20%
SMILES字符串
O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)C(=O)O)O[C@@H]3[C@@](C4[C@@](C5[C@]([C@@]6(C[C@H]([C@]7([C@H]([C@@H](C(CC7C6=CC5)(C)C)OC(=O)\C(=C/C)\C)OC(=O)C)CO)O)C)(CC4)C)(CC3)C
InChI key
AXNVHPCVMSNXNP-ZELRDNAQSA-N
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一般描述
皂苷是一种天然的甾体糖苷（萜烯）。
应用
来自 皂树 树皮的皂苷已被用于：
- 对CD4+ 和CD8+ T细胞进行染色
- 裂解滋养体感染的红细胞
- 免疫组织化学染色中
生化/生理作用
皂苷与许多生物学和药理学活性有关。其已知可在哺乳动物中刺激免疫应答。因此它可用作疫苗佐剂。皂苷具有抗病毒、抗真菌、抗肿瘤、抗炎、降血糖和降胆固醇的作用。
皂苷可溶解胶束中胆固醇的低密度脂蛋白（LDL）部分，从而降低其浓度。来自 皂树 树皮的皂苷可用作食品和饮料中的调味剂。皂苷已在体外被证明可增强免疫细胞增殖。
静脉注射时强效溶血；表面活性剂（增强蛋白质和其他大分子对细胞膜的渗透）;它也被用作疫苗的佐剂。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Joo Young Park et al.
Journal of hazardous materials, 163(2-3), 761-767 (2008-08-12)
The applicability of microbubble suspension made of saponin as a biodegradation-enhancing carrier where oxygen and pollutant-degraders are limited was studied. The saponin-microbubble suspension was used to deliver phenanthrene-degrading bacteria, inorganic nutrients, and oxygen. Bench-scale study was carried out to determine
Samantha Reiss et al.
PloS one, 12(10), e0186998-e0186998 (2017-10-25)
The identification and study of antigen-specific CD4 T cells, both in peripheral blood and in tissues, is key for a broad range of immunological research, including vaccine responses and infectious diseases. Detection of these cells is hampered by both their
Metabolite profiling of the intraerythrocytic malaria parasite Plasmodium falciparum by (1)H NMR spectroscopy.
Teng R
Nmr in Biomedicine, 22(3), 292-302 (2009)
Natalie J Spillman et al.
Molecular and biochemical parasitology, 162(1), 96-99 (2008-08-05)
The intraerythrocytic malaria parasite, Plasmodium falciparum maintains an intracellular pH (pH(i)) of around 7.3. If subjected to an experimentally imposed acidification the parasite extrudes H(+), thereby undergoing a pH(i) recovery. In a recent study, Bennett et al. [Bennett TN, Patel
Effect of testosterone on insulin stimulated IRS1 Ser phosphorylation in primary rat myotubes--a potential model for PCOS-related insulin resistance.
Allemand MC
PLoS ONE, 4(1), e4274-e4274 (2009)
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