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Merck
CN

S6635

Sigma-Aldrich

Span® 20

greener alternative
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别名:
脱水山梨醇单月桂酸酯, 脱水山梨醇月桂酸酯
CAS号:
EC 号:
MDL编号:
UNSPSC代码:
12161900
PubChem化学物质编号:
NACRES:
NA.25

描述

non-ionic

质量水平

分子量

346.47 g/mol

环保替代产品特性

Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

浓度

≥44% (GC)

环保替代产品分类

SMILES字符串

CCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O

InChI

1S/C18H34O6/c1-2-3-4-5-6-7-8-9-10-11-16(21)23-13-15(20)18-17(22)14(19)12-24-18/h14-15,17-20,22H,2-13H2,1H3/t14-,15?,17+,18+/m0/s1

InChI key

LWZFANDGMFTDAV-WYDSMHRWSA-N

一般描述

Span 20是辅助表面活性剂。
我们致力于为您提供更环保的替代产品,以符合“绿色化学的 12 项原则”的一项或多项原则要求。本产品是100%的生物基非离子表面活性剂,因此符合“使用可再生原料”原则,属于我们绿色替代产品中的“12原则产品”。

应用

Span 20已用于评估伊曲康唑的增溶性和口服生物利用度的研究。 其还可用于研究水包油乳液中不饱和脂质的氧化。

其他说明

脂肪酸组成:月桂酸(C12:0)≥44%;平衡主要是肉豆蔻酸(C14:0)、棕榈酸(C16:0)和亚麻酸(C18:3)酸。

法律信息

Span is a registered trademark of Croda International PLC

WGK

WGK 1

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

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Claire Berton et al.
Journal of colloid and interface science, 377(1), 244-250 (2012-04-25)
The development of lipid oxidation in oil-in-water (O/W) emulsions is widely influenced by the properties of the interfacial layer, which separates the oil and water phases. In this work, the effect of the structure of the interface on the oxidative
Muhammad Moniruzzaman et al.
Journal of colloid and interface science, 352(1), 136-142 (2010-09-10)
In this paper, we report a novel ionic liquid-in-oil (IL/o) microemulsion which is able to dissolve pharmaceuticals that are insoluble or sparingly soluble in water and most of pharmaceutical grade organic liquids. Towards this approach, the nanometer-sized ionic liquid droplets
Yung-Chih Kuo et al.
Colloids and surfaces. B, Biointerfaces, 76(1), 286-291 (2009-12-17)
This study analyzes the effects of Tween 80 and Span 20 on the electrical interaction between cationic solid lipid nanoparticles (CSLNs) and human brain microvascular endothelial cells (HBMECs). Electrophoretic mobility, zeta potential and fixed charge density of CSLNs and HBMECs
Muhammad Moniruzzaman et al.
International journal of pharmaceutics, 400(1-2), 243-250 (2010-09-04)
Pharmaceutical industries have posed challenges in the topical and transdermal administration of drugs which are poorly soluble or insoluble in water and most of organic solvents. In an approach to overcome this limitation, ionic liquid-in-oil (IL/o) microemulsions (MEs) were employed
Pao-Chu Wu et al.
Drug development and industrial pharmacy, 36(12), 1398-1403 (2010-06-16)
Nicardipine hydrochloride has been used widely for the treatment of angina pectoris and hypertension. Because of its extensive first pass metabolism after oral administration, the transdermal administration of nicardipine microemulsions was developed in this study. Microemulsions consisted of isopropyl myristate

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