所有图片(1)
About This Item
经验公式（希尔记法）:
C41H65N13O10
CAS号:
分子量:
900.04
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.26
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产品名称
物质 P片段 1-7, ≥97% (HPLC)
质量水平
方案
≥97% (HPLC)
表单
powder
组成
Peptide content, ≥65%
颜色
white
UniProt登记号
应用
cell analysis
储存温度
−20°C
SMILES字符串
NCCCCC(NC(=O)C1CCCN1C(=O)C(N)CCCNC(N)=N)C(=O)N2CCCC2C(=O)NC(CCC(N)=O)C(=O)NC(CCC(N)=O)C(=O)NC(Cc3ccccc3)C(O)=O
InChI
1S/C41H65N13O10/c42-19-5-4-12-28(51-37(60)30-13-7-21-53(30)38(61)25(43)11-6-20-48-41(46)47)39(62)54-22-8-14-31(54)36(59)50-27(16-18-33(45)56)34(57)49-26(15-17-32(44)55)35(58)52-29(40(63)64)23-24-9-2-1-3-10-24/h1-3,9-10,25-31H,4-8,11-23,42-43H2,(H2,44,55)(H2,45,56)(H,49,57)(H,50,59)(H,51,60)(H,52,58)(H,63,64)(H4,46,47,48)
InChI key
KPHDBQWTCKBKIL-UHFFFAOYSA-N
基因信息
human ... TAC1(6863)
相关类别
Amino Acid Sequence
Arg-Pro-Lys-Pro-Gln-Gln-Phe
生化/生理作用
应用于孤束核时具有抑制和减缓心率作用的片段
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Anna Carlsson et al.
European journal of pharmacology, 626(2-3), 250-255 (2009-10-20)
We have recently explored the role of the tachykinin substance P neuroactive fragment substance P(1-7) in the mediation of anti-inflammatory effects using a blister model in the rat paw (Wiktelius et al., 2006). We observed that this heptapeptide induced a
Qin Zhou et al.
Peptides, 32(8), 1661-1665 (2011-07-19)
The N-terminal substance P fragment SP(1-7) is known to modulate hyperalgesia and opioid withdrawal in animal models. This study examined the effects of intraperitoneal (i.p.) injections of SP(1-7) on chronic morphine tolerance and on the levels of dynorphin B (DYN
Qin Zhou et al.
Peptides, 25(11), 1951-1957 (2004-10-27)
The aminoterminal fragment of substance P (SP), SP(1-7), has been suggested to modulate the expression of opiate tolerance and withdrawal behaviors in rodents. However, the mechanism of this effect is not yet clarified. Using a rat model we have previously
Takaaki Komatsu et al.
Neuropharmacology, 61(4), 608-613 (2011-05-24)
Previous research has demonstrated that substance P N-terminal fragments produced by the action of several different enzymes in the spinal cord could reduce nociception when injected intrathecally (i.t.) into mice. The present study examined the possible involvement of spinal extracellular
Qin Zhou et al.
Neuroscience letters, 320(3), 117-120 (2002-02-20)
The biologically active substance P (SP) N-terminal metabolite SP(1-7) has been reported to modulate several neural processes such as learning, locomotor activity and reaction to opioid withdrawal. Although all these processes are believed to be associated with dopaminergic transmission no
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